Many medications interact with each other, and CBD is no exception. These interactions aren’t limited to prescription drugs—over-the-counter medications, dietary supplements, and herbal remedies can also lead to adverse reactions when combined with CBD and cannabis in Maryland.
CBD interacts with several common medications, and its effects can vary depending on the dosage and combination. Before making any changes to your medication routine, it’s crucial to understand the potential consequences. Always consult your healthcare provider before making any decisions.
1. Opioids
Opioids are commonly prescribed for pain relief, especially for chronic conditions. However, they come with risks, including drowsiness, euphoria, dependence, and overdose.
CBD and cannabis in Maryland are increasingly being used as a natural alternative for pain management. Under medical supervision, patients may use CBD to supplement or reduce opioid use. Compared to opioids, CBD:
Is non-addictive
- Does not produce a “high”
- Cannot cause a life-threatening overdose
- Has never been linked to fatality
However, both opioids and CBD can cause drowsiness. Using them together may intensify fatigue to unsafe levels. If considering CBD to reduce opioid use, consult your healthcare provider to create a safe transition plan.
2. Antidepressants (SSRIs)
CBD can interact negatively with selective serotonin reuptake inhibitors (SSRIs), a common class of antidepressants, including:
- Zoloft
- Lexapro
- Prozac
Both CBD and SSRIs can relieve anxiety and depression, but they also share side effects. When taken together, they may intensify symptoms such as sleep disturbances and stomach discomfort—an effect known as “doubling.”
Potential reasons for these intensified effects include:
- Altered metabolism – CBD may interfere with how the body processes SSRIs, leading to higher-than-normal drug levels and increased side effects.
- Lowered blood sodium levels – CBD may reduce blood sodium when combined with sertraline (Zoloft), potentially impairing cognitive function.
Since research on CBD-SSRI interactions is still developing, speak with your healthcare provider before making any changes to your treatment plan.
3. Warfarin and Other Blood Thinners
Studies have shown that CBD and cannabis in Maryland can significantly alter the concentration of Warfarin, a common blood thinner, in the body. This can lead to dangerous fluctuations in effectiveness.
Other medications that CBD may impact similarly include:
- Amiodarone
- Levothyroxine
- Clobazam
- Lamotrigine
- Valproate
If you take any of these medications, consult your doctor before incorporating CBD into your routine. Never adjust your dosage or stop taking prescribed medications without professional guidance.
4. Antihistamines
Antihistamines help manage allergy symptoms like congestion, sneezing, and itching. Some, like diphenhydramine (Benadryl), can also cause drowsiness. When combined with CBD, sedative antihistamines may intensify drowsiness, leading to:
- Excessive fatigue
- Dizziness
- Confusion
- Impaired focus
Since CBD also addresses symptoms like inflammation and nausea, some people consider it an alternative to antihistamines. If you’re interested in making a switch, consult your healthcare provider.
5. Melatonin
Melatonin supplements are used to promote sleep. Since CBD also has calming effects, combining the two may enhance drowsiness to an excessive degree. While studies on CBD and melatonin interactions are limited, their shared properties suggest that combining them may increase risks such as:
- Confusion
- Dizziness
- Impaired concentration
Similar effects may occur when combining CBD with other sedating substances, including:
- Kava
- St. John’s Wort
- Valerian
- L-Tryptophan
- Alcohol
Some products even blend CBD and melatonin for enhanced sleep support. However, to determine the best sleep aid for your needs, consult your healthcare provider.
CBD has the potential to provide therapeutic benefits, but it can also interact with many medications. If you’re considering incorporating CBD into your routine, it’s essential to do so under medical supervision. Always discuss potential interactions and adjustments with your healthcare provider to ensure your safety and well-being.
CBD and Cannabis in Maryland
Dispensary Works is a Southern Maryland marijuana dispensary committed to providing the best cannabis product to patients and clients. Our highly trained staff is here to help you select the best cannabis for your particular needs. We are here to guide you as you uncover the world of marijuana. If you would like to learn more about who we are and what we do, contact us today!
